The Chefs have shown they can adapt to shut-down the primary attack...like Derrick Henry.
but the Niners have such a variety of attacks, all centered around limiting the possessions of the other team, that I don't know if the Chiefs will be able to adapt quickly enough to keep the Niners from scoring. Mahomie's come-backs are predicated on the D shutting down the scoring weapons of the other team...
But Mostert, Kittle, He-Manuel, Deebo, Jusckcvnboabnnfrcyck...that's a tall order.
I had Kelce for fantasy this year, he's a killer. The Niners have some fast LBs and Jimmie Ward will wreck shop out of the FS spot...people forget he was a LB in college. like you said, who can get the match-up they want and actually exploit it.
But I know the NFL in the Roger Goodell era is perfectly OK with putting their thumb on the scales, so I'm not getting too excited.