General Study: Ivermectin doesn’t do jackshit in the treatment of Covid

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Splinty

Shake 'em off
Admin
Dec 31, 2014
44,116
91,101
Vents are counterproductive.
75% of vent parients are dead.
100% are dead with out.
With a po2 40 and a PCO2 of 90 and tachypneic at 35, Should I just sit there and watch them guppy until they die?

What you missed out on the ventilator conversation is two distinct phenotypes of ventilation perfusion compromise in covid. You've only memorized that there are a portion that risk baro trauma following ardsnet protocols. You've forgotten that there's a whole other that are proper ARDS.
And in both cases you're dead without the vent. It's just two different ventilator strategies.
 

Splinty

Shake 'em off
Admin
Dec 31, 2014
44,116
91,101
You're saying that 10's of thousands of people have NOT died due to the vax, correct?

Correct.
There is not evidence for that right now.



This is actually probably the only thing I would entertain so far in this thread.
Could I imagine that we would continue pushing a vaccine that killed 20,000 in 2.5 billion injections?

Yeah. That's 0.000008% chance of death. I could see that taking a long time to be confirmed.

On the other hand I've paid attention to your previous post on this topic with references to things like this:
so come correct with something new besides VAERS
 

MMAPlaywright

First 100
First 100
Jan 18, 2015
6,030
10,717
Double negative in title so it actually do something
Not a double negative. It’s a statement that it doesn’t do jackshit. “Jackshit” is a very low threshold, but a tad more than zero. Ivermectin purported benefits don’t rise to the level of jackshit.

WTF am I wasting my time trying to explain this to a 90 year old?
 

BeardOfKnowledge

The Most Consistent Motherfucker You Know
Jul 22, 2015
60,554
56,278
Not a double negative. It’s a statement that it doesn’t do jackshit. “Jackshit” is a very low threshold, but a tad more than zero. Ivermectin purported benefits don’t rise to the level of jackshit.

WTF am I wasting my time trying to explain this to a 90 year old?
Because you respect your very, very, very, very, very.....very elders.
 

sparkuri

Pulse On The Finger Of The Community
First 100
Jan 16, 2015
35,484
47,345
100% are dead with out.
With a po2 40 and a PCO2 of 90 and tachypneic at 35, Should I just sit there and watch them guppy until they die?

What you missed out on the ventilator conversation is two distinct phenotypes of ventilation perfusion compromise in covid. You've only memorized that there are a portion that risk baro trauma following ardsnet protocols. You've forgotten that there's a whole other that are proper ARDS.
And in both cases you're dead without the vent. It's just two different ventilator strategies.
Lol, that's not true!

I posted in the coronavirus thread this week about a woman who refused ventilator in the ICU, demanded her treatment for her husband, and he WALKED out in 3 days!
A hospital record!

That happened this week!

The treatment guidelines are designed for death, and handed down by bureaucrats.
Even Dr.Drizzy's chiming in with a 180.


View: https://youtu.be/lijS4CuMRH0
 

Qat

QoQ
Nov 3, 2015
16,385
22,624
Eudraviligence
For the record, sparkuri @sparkuri has probably never run the numbers of Eudravigilence on the vaccines himself.

He however posted a link to a questionable source claiming to have run em, and he even quoted that source incorrectly on here by claiming the total amount of adverse effects (so mild included) as serious cases, when in fact serious cases are a distinct and different number.

He can't read my post so it's just for info for anyone taking his numbers into account.

 

kneeblock

Drapetomaniac
Apr 18, 2015
12,435
23,026
100% are dead with out.
With a po2 40 and a PCO2 of 90 and tachypneic at 35, Should I just sit there and watch them guppy until they die?

What you missed out on the ventilator conversation is two distinct phenotypes of ventilation perfusion compromise in covid. You've only memorized that there are a portion that risk baro trauma following ardsnet protocols. You've forgotten that there's a whole other that are proper ARDS.
And in both cases you're dead without the vent. It's just two different ventilator strategies.
Stylin on em.
 

Dick Niaz

Yearning for TMMAC days gone by
Jan 14, 2018
12,278
25,558
The key at this point is keeping patients out of the hospital by starting treatment early in disease progression. If vaccination rates are going to remain subpar (which is a certainty due to the insanity that they have somehow become politicized and public health statements get bastardized by narratives), then earlier treatment needs to be the focus.
Monoclonal antibodies (mAb) are severely underutilized right now. Early studies looked at their efficacy in progressive stages of disease, where they didn’t fare so well. When studies looked at their ability to prevent that disease progression and keep people out of the hospital, they performed tremendously. The Lilly product was pulled from its EUA (emergency use authorization) but the Regeneron and GlaxoSmithKline options are faring very well against the currently most common variants, including Delta. Due to the guardrails of my position, I can’t get into some of the confidential details about what is to come, but I can say that there will be new presentations of the mAbs which will make administration and site of care more efficient. Also, with the emerging variants that will inevitably make up a higher percentage of cases in the coming months/year, there will be further differentiation within the available mAbs as far as efficacy, but the good news is there will be at least one option that shows efficacy against the next few which are most likely to emerge (at least in the US. There will continue to be variability in rates/variant globally).
 

Shinkicker

For what it's worth
Jan 30, 2016
10,325
13,933
Does that lady have a meta-analysis?
If she's an expert at studies review and guideline creation, does she have a review printed that has proper inclusion and exclusion criteria to help cut through "the noise" referenced?

She is Theresa Lawrie
 

Splinty

Shake 'em off
Admin
Dec 31, 2014
44,116
91,101

She is Theresa Lawrie

That's a reasonably well put together meta-analysis. Probably the most convincing compilation so far.
I wonder what the analysis looks like if you drop the three or four most risk bias studies.

I'm on the go but will have to pull up those higher quality studies she's references.

"You can hide anything under a meta-analysis" is a known axiom, but they exist for a reason.
 
M

member 1013

Guest
For the record, sparkuri @sparkuri has probably never run the numbers of Eudravigilence on the vaccines himself.

He however posted a link to a questionable source claiming to have run em, and he even quoted that source incorrectly on here by claiming the total amount of adverse effects (so mild included) as serious cases, when in fact serious cases are a distinct and different number.

He can't read my post so it's just for info for anyone taking his numbers into account.

Have u doe?!?
 

Splinty

Shake 'em off
Admin
Dec 31, 2014
44,116
91,101
The key at this point is keeping patients out of the hospital by starting treatment early in disease progression. If vaccination rates are going to remain subpar (which is a certainty due to the insanity that they have somehow become politicized and public health statements get bastardized by narratives), then earlier treatment needs to be the focus.
Monoclonal antibodies (mAb) are severely underutilized right now. Early studies looked at their efficacy in progressive stages of disease, where they didn’t fare so well. When studies looked at their ability to prevent that disease progression and keep people out of the hospital, they performed tremendously. The Lilly product was pulled from its EUA (emergency use authorization) but the Regeneron and GlaxoSmithKline options are faring very well against the currently most common variants, including Delta. Due to the guardrails of my position, I can’t get into some of the confidential details about what is to come, but I can say that there will be new presentations of the mAbs which will make administration and site of care more efficient. Also, with the emerging variants that will inevitably make up a higher percentage of cases in the coming months/year, there will be further differentiation within the available mAbs as far as efficacy, but the good news is there will be at least one option that shows efficacy against the next few which are most likely to emerge (at least in the US. There will continue to be variability in rates/variant globally).

The future in so much of medicine is synthetic antibodies and mRNA vaccines.
100 years from now they're going to look back at the drugs I give that are not targeted and it will be thought of like leeches.
 

Qat

QoQ
Nov 3, 2015
16,385
22,624
Have u doe?!?
Yes, about two months ago for one vaccine (the one I was going to get).

But it's a lot of work and you have to take it with a grain of salt as well since none of the data is vetted, and only about half is actually reported by medical personnel.

And ofc the numbers are ever-changing, so two months ago doesn't mean much now.
 
M

member 1013

Guest
Yes, about two months ago for one vaccine (the one I was going to get).

But it's a lot of work and you have to take it with a grain of salt as well since none of the data is vetted, and only about half is actually reported by medical personnel.

And ofc the numbers are ever-changing, so two months ago doesn't mean much now.
U never did a science thing in ur life bruv!