good postwell of course you're giving me a 24-hour range. Let's talk about just back-to-back test.
Since there are false positives and false negatives that can exist.
You could have your example or vice versa.
Swapping technique by the tech could change things as well as viral shedding if you're going entire 24 hours.
I think the much larger problem is what do I do with somebody who's positive but their symptoms have improved? If I am swabbing you 3 weeks later and you have symptoms and your positive I feel like I'm learning something about the disease. This has occurred with my patients.
I then have that patient back and swapped them again a week later and they're still positive but their fever broke three days before. Are they still shedding enough to infect others? they're probably shedding enough for me to pick up on a test but I don't know when I clear them. So I sit on them for a week and then test them a week later and they're asymptomatic and they're test becomes negative.
I will tell you that in my own small experience I do see on these longer cases positive positive positive positive positive than negative. And typically you know it's going to become negative because their fever has broken and they just constitutionally feel better in general.
PCR?
Well as above it's not. Like all of clinical medicine I test is best when it just simply confirms what you already know.
After I've seen enough patients I will tell you that I can spot the symptomatic Corona viruses in the mix. They stand out for this time of the year.
But in my example above where somebody has this window where I can still find virus but I am a few days after their symptoms have abated, are they still shedding?
Lotta questions to be answered still
Yes, Kary Mullis(Scientist) would likely not approve of his test(PCR) being used in it's current application. RIP tho.