General COVID Darwin Awards

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BeardOfKnowledge

The Most Consistent Motherfucker You Know
Jul 22, 2015
60,656
56,174
They are making an omicron specific vaccine but it'll be available after the USA has peaked with omicron so lol whatevs GG Pfizer.
This is mind boggling to me. I'm just coming up on 6 months out from second dose and was like "They'll have an omicron vaccine by March? I might as well just wait, and get the one I actually need." Then Health Canada is like "Well, we're actually going to trial this one." Ffs.
 

Splinty

Shake 'em off
Admin
Dec 31, 2014
44,116
89,915
This is mind boggling to me. I'm just coming up on 6 months out from second dose and was like "They'll have an omicron vaccine by March? I might as well just wait, and get the one I actually need." Then Health Canada is like "Well, we're actually going to trial this one." Ffs.

Beyond my understanding of what to do locally or what's going on in the United States, there's probably some utility in targeting this strain throughout the world to lower future variants. But it is pretty ironic that we just keep bringing out the technologies just in time to no longer work or after they arent clinically relevant for most of us
 

BeardOfKnowledge

The Most Consistent Motherfucker You Know
Jul 22, 2015
60,656
56,174
Beyond my understanding of what to do locally or what's going on in the United States, there's probably some utility in targeting this strain throughout the world to lower future variants. But it is pretty ironic that we just keep bringing out the technologies just in time to no longer work or after they arent clinically relevant for most of us
What I find the most interesting thing of MRNA tech is that it's written like a computer code (yes, this a complete laymen's understanding), so they can just go "Oh, make "that" a "this" and we're good to go." but government bureaucracy is apparently going to prevent that from being feasible going forward.
 

Rambo John J

Baker Team
First 100
Jan 17, 2015
75,366
74,511
What I find the most interesting thing of MRNA tech is that it's written like a computer code (yes, this a complete laymen's understanding), so they can just go "Oh, make "that" a "this" and we're good to go." but government bureaucracy is apparently going to prevent that from being feasible going forward.
You want less regulation and safety testing? While maintaining no responsibility for damage caused ?
 

Splinty

Shake 'em off
Admin
Dec 31, 2014
44,116
89,915
What I find the most interesting thing of MRNA tech is that it's written like a computer code (yes, this a complete laymen's understanding), so they can just go "Oh, make "that" a "this" and we're good to go." but government bureaucracy is apparently going to prevent that from being feasible going forward.
So that's part of it and I agree. Lots of biotech is moving at light speed and I'm not sure the government bureaucracy is ready for it. Antibodies and mRNA are good examples where things are going to keep advancing really quickly.

But also we have to be very careful. You are taking MRNA and print a protein from it. That protein then has to fold. It does that with physics, not our influence. We are getting better and better and predicting protein folding but that ain't nothing. Still have to make sure that you don't have adverse reactions from antigenic responses that are unexpected. In that problem gets even more complex when you start targeting multiple antigens. One of the reasons our vaccines continue to seem weaker and weaker is that we are only targeting the spike protein. If we targeted multiple proteins, we wouldn't have such an easy time mutating around the vaccines pressures. But then you have a more complex problem predicting protein folding and then the biologic response to those generated proteins.

I'm of course not a biochemist and I'm not sure how close we are to predicting this stuff with 100% accuracy on the first go with computer modeling. But my understanding as we aren't there yet.
 

John Lee Pettimore

Further south than you
May 18, 2021
6,302
6,718
"We are aggressively
You want less regulation and safety testing? While maintaining no responsibility for damage caused ?
He doesn't want anything except to bitch all the time, about literally anything that any government or public health organisation says or does or tries to do.

??
 

BeardOfKnowledge

The Most Consistent Motherfucker You Know
Jul 22, 2015
60,656
56,174
I'm of course not a biochemist and I'm not sure how close we are to predicting this stuff with 100% accuracy on the first go with computer modeling. But my understanding as we aren't there yet.
Uh. You know this is the internet, right?
 

BeardOfKnowledge

The Most Consistent Motherfucker You Know
Jul 22, 2015
60,656
56,174
Where everything is true and watching YouTube videos is the same as a PhD ?
Let me help you out here.

I watched a YouTube video by a guy who once met a biochemist at Starbucks and I'm pretty sure we're close to predicting this stuff with 100% accuracy on the first go with computer modeling. My understanding as that we are right there.
 

BeardOfKnowledge

The Most Consistent Motherfucker You Know
Jul 22, 2015
60,656
56,174
If you're referring to a critically vulnerable father of a young child refusing to get vaccinated so that he can have a heart transplant, I agree. He's a fucking moron.
I was actually referring to giving someone a death sentence based on vaccination status.
 

Leigh

Engineer
Pro Fighter
Jan 26, 2015
10,925
21,023
I was actually referring to giving someone a death sentence based on vaccination status.
That's what I thought and I completely disagree with you. They responded to their reasoning, which is in line with organ transplant protocol throughout history; organs are limited and will go to people who need them the most and who have the greatest chance of survival.


The hospital said it was following policy.
Brigham and Women's Hospital told the BBC in a statement: "Given the shortage of available organs, we do everything we can to ensure that a patient who receives a transplanted organ has the greatest chance of survival."
A spokesman said the hospital requires "the Covid-19 vaccine, and lifestyle behaviours for transplant candidates to create both the best chance for a successful operation and to optimise the patient's survival after transplantation, given that their immune system is drastically suppressed".
The hospital's carefully worded statement may suggest other factors lie beyond the patient's unvaccinated status for his ineligibility, but it refused to discuss specifics, citing patient privacy.
The hospital added that most of the 100,000 people on waitlists for organ transplants will not receive an organ within five years because of the shortage of available organs.
 

BeardOfKnowledge

The Most Consistent Motherfucker You Know
Jul 22, 2015
60,656
56,174
That's what I thought and I completely disagree with you. They responded to their reasoning, which is in line with organ transplant protocol throughout history; organs are limited and will go to people who need them the most and who have the greatest chance of survival.
I'm a world where being a full blown alcoholic doesn't disqualify you from receiving a liver transplant, their rationalization claims don't hold water.

Also, didn't the UK just ditch vaccine mandates?
 

Leigh

Engineer
Pro Fighter
Jan 26, 2015
10,925
21,023
I'm a world where being a full blown alcoholic doesn't disqualify you from receiving a liver transplant, their rationalization claims don't hold water.

Also, didn't the UK just ditch vaccine mandates?
Government vaccine mandates aren't relevant to medical decisions.

Alcoholics getting liver transplants are different. Whilst I agree it should be a factor, alcoholism is a recognised condition. Refusing vaccination is not. George Best was an alcoholic and got liver transplant. After he destroyed that one, he didn't get another.

I think for the purpose of honest discussion, it should be noted that this father claims not to be antivax but has concerns that the covid vaccines could damage his already failing heart.
 

BeardOfKnowledge

The Most Consistent Motherfucker You Know
Jul 22, 2015
60,656
56,174
Government vaccine mandates aren't relevant to medical decisions.

Alcoholics getting liver transplants are different. Whilst I agree it should be a factor, alcoholism is a recognised condition. Refusing vaccination is not. George Best was an alcoholic and got liver transplant. After he destroyed that one, he didn't get another.

I think for the purpose of honest discussion, it should be noted that this father claims not to be antivax but has concerns that the covid vaccines could damage his already failing heart.
Given what we know that seems like a somewhat legitimate concern does it not? Everyone who gets vaccinated runs the Rick of side effects, but not everyone is going to get COVID.

That being said, alcoholism being a recognized condition is not relevant to whether or not the policy is illogical.
 

Leigh

Engineer
Pro Fighter
Jan 26, 2015
10,925
21,023
Given what we know that seems like a somewhat legitimate concern does it not? Everyone who gets vaccinated runs the Rick of side effects, but not everyone is going to get COVID.

That being said, alcoholism being a recognized condition is not relevant to whether or not the policy is illogical.
Neither of us are doctors. These are the points, they make the decisions based on their experience and knowledge. Mathematically, your risk of getting covid and myocarditis is significantly higher than myocarditis from a vaccine.

You don't understand that there might be more flexibility with someone who has an addiction over someone who is being obstinate? Ok but that's a you issue.
 

BeardOfKnowledge

The Most Consistent Motherfucker You Know
Jul 22, 2015
60,656
56,174
Neither of us are doctors. These are the points, they make the decisions based on their experience and knowledge. Mathematically, your risk of getting covid and myocarditis is significantly higher than myocarditis from a vaccine.

You don't understand that there might be more flexibility with someone who has an addiction over someone who is being obstinate? Ok but that's a you issue.
Is a flu vaccine a requirement? Because that would check all the same boxes.

I also realize neither of us are doctors. I didn't think that needed to be said. I do think you might be conflating bureaucratic decisions with scientific ones.
 

Filthy

Iowa Wrestling Champion
Jun 28, 2016
27,507
29,640
Beyond my understanding of what to do locally or what's going on in the United States, there's probably some utility in targeting this strain throughout the world to lower future variants. But it is pretty ironic that we just keep bringing out the technologies just in time to no longer work or after they arent clinically relevant for most of us
it's ironic that the BigPharma solutions keep the pandemic going?

not sure you're using "ironic" correctly.
 

Filthy

Iowa Wrestling Champion
Jun 28, 2016
27,507
29,640
Is a flu vaccine a requirement? Because that would check all the same boxes.

I also realize neither of us are doctors. I didn't think that needed to be said. I do think you might be conflating bureaucratic decisions with scientific ones.
trying to talk science is just going to get you "drunk" ratings with this one.

enjoy.