For the Brit who has never tested positive himself, but has fought a who's who list of opponents either using banned or controversial substances - and, as aforementioned, whose career has been affected by the prevalence of opponents using - he simply could not contain his noticeable disdain.
"And I just want to say something," Bisping notes. "Yeah, we're all chasing a dream. All fighters have a dream, a dream of being the champion. You gotta do it through hard work and determination. The fact of the matter is Anderson Silva tested positive for not one, not two, but three banned substances inside his body.
"While I respect him as a fighter, I've gotta say, I lost a lot of respect for him for that," he continues. "This fight represents me beating all of these people that want to cheat the system. I've never taken performance enhancing drugs in my life. Anybody that does should be ashamed. To call yourself a martial artist and to take performance-enhancing drugs is the biggest contradiction you could ever make. And to be honest, Anderson should be ashamed of himself."
For Bisping, Silva being bothered with his Twitter comments is must-mention material.
"[PED use in MMA] is something I am quite emotional about because it blows my mind," he began. "To be quite frank, I'm blown away by his arrogance. How on earth do you expect me not to mention that in your last fight, you tested positive for three banned substances? You expect me to not mention that?
LINK: Michael Bisping: 'I'm blown away' by Anderson Silva's 'arrogance' in PED use denial